From the very beginning of the use of this plant, consumers were not very interested in its composition. They were content to take advantage of its effects. However, as Kratom grew in popularity, it began to attract attention. Several studies have been carried out on the plant, including research into its chemical constituents. The studies show that the plant contains around 25 alkaloids. Which chemical components are represented in higher doses?
While it was thought that mitragynine was the most represented alkaloid in Kratom production, this has rather changed since 2020. According to research conducted by a group of Japanese researchers, 7-hydroxymitragynine is the most potent component of this plant. If you want to know how representative each of the chemicals in Kratom is, visit https://www.tips-of-the-day.com/. Obviously, from the studies done on all the alkaloids found in this plant, it is published that 7-hydroxymitragynine is 30 times more potent than mitragynine. This means that desapite its low concentration in Kratom, this substance relegates mitragynine and all other chemicals to the background. However, although it interacts with all opioid sites, 7-hydroxymitragynine remains more attached to Mu receptors.
Mitragynine is a major player in Kratom. It has the recreational properties and still remains the single most prevalent substance in the production of this plant. It alone accounts for 60% of the chemical composition of Kratom. Mitragynine is actually a stimulant that interacts with the Delta receptor when used in low doses. At higher doses, it interacts with the Mu receptors.